IL1 Nitric oxide as a mediator of erectile function
نویسندگان
چکیده
منابع مشابه
Nitric oxide as a mediator of delayed pharmacological (A receptor
Background: Nitric oxide (NO), synthesised from the inducible isoform of nitric oxide synthase (iNOS), is implicated in mediating second window of protection (SWOP)/delayed ischemic preconditioning. However the role of NO and iNOS in delayed pharmacological protection remains unclear and is the subject of this investigation. Methods: To test the hypothesis that iNOS is necessary for delayed 6 p...
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Part of the regulation of gastrointestinal (GI) smooth muscles is provided by nonadrenergic noncholinergic (NANC) nerves. Stimulation of these nerves, either by field stimulation or via neural reflex pathways, elicits hyperpolarization of postjunctional smooth muscle membranes referred to as inhibitory junction potentials and relaxation. The transmitter(s) that mediate NANC inhibitory neural tr...
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Inflammation influences the development of cancer. The nitric oxide synthase (NOS2) is induced by inflammatory cytokines, e.g., tumor necrosis factor alpha and interleukin 1beta, and produces nitric oxide (NO*), a critical mediator of the inflammatory response. Because p53 governs NO* production by transcriptionally transrepressing NOS2, we used a genetic strategy to determine whether NO* and p...
متن کاملNitric Oxide is a Paracrine Mediator of Ultraviolet-induced Melanogenesis
Ultraviolet (UV) radiation is the main physiological stimulus for human skin pigmentation. Within the epidermalmelanin unit, melanocytes synthesize and transfer melanin to the surrounding keratinocytes. Keratinocytes produce paracrine factors that affect melanocyte proliferation, dendricity, and melanin synthesis. In this report, we show that normal human keratinocytes secrete nitric oxide (NO)...
متن کاملEffects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats.
AIM To investigate the effect of icariin on erectile function and the expression of nitric oxide synthase (NOS) isoforms in castrated rats. METHODS Thirty-two adult male Wistar rats were randomly divided into one sham-operated group (A) and three castrated groups (B, C and D). One week after surgery, rats were treated with normal saline (groups A and B) or oral icariin (1 mg/[kg.day] for grou...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 2011
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol.102.63